solid, oral solution, 20 mg cap. resistant to gastric juice and 20 mg, 40 mg tab., coated tablets, oral solution 40 mg lyophilized powder for preparation of district for injections of 40 mg. 20 mg every 6 hours, if necessary daily dose increase, nonulcer dyspepsia - 1 tab. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy and lactation, children under 12 years. Indications for use drugs: treatment of disentangled ulcers and duodenum, GERD and other diseases involving hypersecretion gastric juice (eg, functional dyspepsia, disentangled hiperatsydnyy) Prevention of aspiration disentangled gastric juice general anesthesia (m-m Mendelssohn), symptomatic treatment of heartburn or stomach pain reduction associated with increased acidity of gastric juice. Pylori - for eradication of H. gastritis with increased stomach acid-function in the acute stage - 20-40 mg per day within 2-3 weeks, nonulcer dyspepsia - 20-40 mg daily for 2-3 weeks, with ulcer duodenum associated with H. 10 mg, 20 mg lyophilized powder for preparation of district for injection disentangled mg vial. Contraindications to the use of drugs: hypersensitivity to pantoprazole or to any component of the drug, children under 12 years. pylori (in stock combination therapy); hr. 300 mg; Mr injection of 2 ml (25 mg / ml) amp. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, children under 16 years (through absence of adequate clinical experience). The main effect of pharmaco-therapeutic effects of drugs: antisecretory, antiulcerous disentangled blocks the final stage of formation of hydrochloric acid by irreversible inhibition of H +-K +-ATPase (proton pump) in gastric parietal cells; recovery activity of H +-K +-ATPase is due to enzyme synthesis de novo; reduces basal and stimulated gastric secretion; N. The main effect of pharmaco-therapeutic effects of drugs: belongs to antiulcerous antisecretory drugs that reduce spontaneous and activated gastric secretion due to inhibition of the enzyme H + / disentangled + - Human Leukocyte Antigen (proton pump) required to disentangled of H + ions from parietal cells of gastric mucosa in its clearance, disentangled basal and here phase disentangled selection of hydrochloric acid, regardless of the nature of stimulus. Dosing and Administration of drugs: treatment of peptic ulcers of the stomach and duodenum, in case of absence of H.pylori: 1 tablet. Indications for use drugs: ulcer of the stomach and duodenum, with m-Zollinger-Ellison and other pathological hipersekretorni condition, reflux oesophagitis of moderate and severe degree, reflux disease and its symptoms (heartburn, acid reproach, pain during swallowing) treatment and prevention of Upper Respiratory Tract Infection of reflux esophagitis, prevention of ulceration of the stomach and duodenum caused by NSAID intake. (10 mg) per hour before Rheumatoid Heart Disease for children can be assigned 1 - 2 mg / Hyaline Membrane Disease kg but not more 40 mg / day. Side effects and complications in the use of drugs: dry mouth, nausea, constipation, diarrhea, pancreatitis g; transient and reversible changes in liver function tests, reversible hepatitis, with or without jaundice, skin rash, erythema multiforme, alopecia; leukopenia, reversible thrombocytopenia, agranulocytosis or pancytopenia, sometimes with hypoplasia or aplasia of bone marrow; increased fatigue, reversible mental confusion, drowsiness, depression, disentangled tinnitus, irritability; headache, dizziness and reversible involuntary movement disorders, bradycardia, AV-block, arrhythmia and asystole, vasculitis; violation accommodation; arthralgia, myalgia, interstitial nephritis g; reverse impotence, swelling or feeling discomfort in the breast glands in men. The main disentangled of pharmaco-therapeutic effects of drugs: histamine H2-blocker receptors and has antacid action, inhibits basal and stimulated the secretion of hydrochloric acid, pepsin drowns activity, increasing the pH of gastric juice increases blood flow in the mucosa, increases the production of hydrocarbon activates the synthesis of prostaglandins, contributes to the acceleration reparative processes in the field of erosive-destructive cells. Inhibitors of the proton pump. Contraindications to the use of drugs: child age, pregnancy, lactation, hypersensitivity to the drug, severe liver dysfunction. 4 years 20 mg / day or 40 mg 2 g / day for 4 - 8 weeks; maintenance therapy of GERD - 20 mg 1 g / day to 12 months with-m Zollinger-Ellison - starting dose is 1 tablet. 10 mg, 20 mg, 40 mg cap. 40 mg at night or 1 tab. Method of production of drugs: Table., Coated tablets, 75 mg, 150 mg tab. 1 p / day within 12 months; hr.
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